The company was founded in 2005 as Berkeley Bionics. It was established in Berkeley, California. Ekso Bionics has thrived the robotics markets through partnerships with more established institutions like UC Berkeley. It was also a recipient of research grants from the Defense Department and licensed technology from Lockheed Martin Corporation. These partnerships and grants have helped Ekso Bionics in its pioneering efforts in exoskeleton.
Among the most celebrated exoskeletons were the Human Universal Load carrier (HULC), which can carry heavy loads and the eLEGS, an intelligent exoskeleton that can help a wheelchair user to stand and walk.